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KMID : 1130320080510020214
Korean Journal of Pediatrics
2008 Volume.51 No. 2 p.214 ~ p.218
Palliative effect of 131I-MIBG in relapsed neuroblastoma after autologous peripheral blood stem cell transplantation
Lee Yong-Jik

Hah Jeong-Ok
Abstract
Neuroblastoma is one of the most common extracranial solid tumor of childhood, and treatment of refractory neuroblastoma remains a significant clinical problem. Iodine-131-metaiodobenzylguanidine (131I-MIBG) therapy is an alternative approach to treat stage ¥³ neuroblastoma. We report the palliative effect of 131I-MIBG in three cases of relapsed neuroblastoma after autologous peripheral blood stem cell transplantation. 131I-MIBG is an effective and relatively nontoxic palliative therapy resulting in reduction of pain and prolongation of survival. (Korean J Pediatr 2008;51:214-218)
KEYWORD
Relapsed neuroblastoma, 131I-MIBG, Palliative therapy
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